Bachelor of Applied Technology - Biotechnology

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  • Objectives
    This program will ready graduates for jobs in growth areas of Applied Biotechnology such as medicine, pharmaceuticals and nutraceuticals, agriculture, bioremediation, research and development. Students will study theoretical molecular biology, microbiology, virology, toxicology; and related societal, economic, ethical, legal, and environmental issues. Graduates will be skilled in the handling of microbial, plant, and animal genetic material and proteins, small animal handling, experimental design, statistical data analysis, and bioinformatics. Throughout the program, students will apply this knowledge to regulatory affairs, quality assurance, bioethics, and biohazard management while developing interpersonal and communication expertise, and the skills necessary for life long learning.
  • Practical experience
    There are four months of mandatory co-op and four months of optional co-op experience during this program.
  • Academic title
    Bachelor of Applied Technology - Biotechnology
  • Course description
    Level 1    Credits
    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • CHEM-7002    Chemistry 1     4.00
    • COMM-7001    Introductory Communications     3.00
    • ENVR-7004    Environmental & World Issues     3.00
    • BIOL-7002    Molecular Biology     3.00
    • MATH-7002    Mathematics 1     3.00

    Level 2    Credits
    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • CHEM-7003    Chemistry 2     4.00
    • PHYS-7001    Physics 1     3.50
    • HIST-7003    History & Philosophy of Sciences     3.00
    • BIOL-7003    Plant & Animal Anatomy & Physiology     4.00

    Level 3    Credits

    Take all of the following Mandatory Courses:
    • CHEM-7004    Analytical Chemistry 1     2.50
    • COMP-7002    Computers & Applications     2.00
    • PHYS-7002    Physics 2     4.00
    • BIOL-7001    Microbiology 1     2.50
    • WRIT-7001    Report Writing     2.00

    Level 4    Credits

    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • BIOL-7004    Genetics     3.00
    • PHYS-7003    Radiation Physics     4.00
    • MATH-7003    Mathematics 2     2.50
    • SFTY-7001    Occupational Health & Safety     2.50
    • CHEM-7005    Organic Chemistry 1     3.00
    • MATH-7004    Statistics & Quality Assurance     2.50

    Level 5    Credits
    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • COMP-7003    Advanced Computer Applications     3.00
    • CHEM-7006    Biochemistry 1     5.00
    • CHEM-7007    Instrumental Chemistry Analysis 1     3.50
    • BIOL-7005    Microbiology 2- Industrial Applications     3.50
    • CHEM-7008    Organic Chemistry 2     3.00
    Level 6    Credits
    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • ZOOL-7001    Animal Care & Handling     2.00
    • BIOL-7006    Applied Molecular Genetics     3.00
    • CHEM-7009    Instrumental Chemistry Analysis 2     3.50
    • PHRM-7002    Pharmacology,Toxicology,& Nutraceutical     3.00
    • COMM-7005    Research & Technical Writing     2.00
    • CHEM-7001    Biochemistry 2     3.50

    Level 7    Credits
    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • CHEM-7010    Analytical Chemistry 2     2.50
    • BIOL-7007    Applied Biotechnology 1     3.50
    • BIOL-7008    Bioinformatics     2.00
    • ENGR-7001    Bioprocess Engineering     3.00
    • SFTY-7002    Biosafety & Regulatory Affair     2.00
    • COMM-7006    Thesis     3.00

    Level 8    Credits
    Gen Ed - Take a 3 credit General Education elective course
    Take all of the following Mandatory Courses:
    • BIOL-7009    Applied Biotechnology 2     3.50
    • BIOL-7010    Bioethics     3.00
    • BIOL-7011    Current Topic in Biotechnology     3.00
    • ECON-7002    Macroeconomics     3.00
    • ENGR-7002    Manufacturing Process Engineering     3.00
    • BIOL-7012    Microbiology 3 (Immunology&Virology)     3.00

    Gen Ed - Electives
    Take 21 General Education Credits -
    Normally taken in Levels 1, 2, 4, 5, 6, 7 and 8

    BIOL-7001 -  Microbiology 1
    This course is an introduction to microbiology. The classification, structure, nutritional requirements, aerobic and anaerobic metabolism, primary and secondary metabolites and diversity of microorganisms is examined. the use of single cells as factories to generate an industrial or clinical product and the environmental implications of their use will be studied. The laboratory components introduce students to aseptic techniques, culturing and microorganism classification in an environment that cultivates an awareness of their potential pathogenic capabilities and biohazard classification.

    BIOL-7002 -  Molecular Biology

    An introduction to the basic biological processes at the cellular and molecular level in prokaryotes and eukaryotes. The cellular structure/function relationship at the macromolecular and genetic levels, DNA structure, chemistry, replication, gene expression and genetic changes are discussed. The laboratories and tutorials compliment the lectures by introducing basic laboratory techniques. Students develop skills in preparation, extraction and separation of cellular components, gel electrophoresis and serial dilutions.

    BIOL-7003 -  Plant & Animal Anatomy & Physiology

    This course studies plant and animal physiology systems. Plant anatomy and physiology, and the role of specific cell types, will be studied in the context of function. Plant embryogenesis, development and growth and the influence of plant hormones on these processes will be examined. Animal organ systems, the cell types which constitute the various systems and how these cell types work together in a functioning organ will be studied. Animal physiology as a function of the organ system will be examined. Animal development from an anatomical and development of organ systems will be studied. The effects of osmotic conditions, the role of junctional complexes, and cell-cell communication in different cell types and how these affect the functioning of tissues as a whole will be studied.

    BIOL-7004 -  Genetics

    In this course, students examine the genetic basis of life including Mendelian and non-Mendelian patterns of inheritance, meiosis and homologous recombination theory and their role as a molecular tool. Gene linkage, linkage analysis, autosomal, single gene, multigene and sex-linked disorders will be investigated. Students will be introduced to the role of transcription factors/transcription factor complexes, regulatory elements and their relationship to the genes they regulate. The structural changes in the DNA associated with these genetic activities will be explored. Prokaryotic and viral genetics and the application of their genes and regulation of their genes as applied to molecular biology will be studied.

    BIOL-7005 -  Microbiology 2- Industrial Applications

    This Industrial Microbiology course explores the application of scientific and engineering principles as applied to the processing of materials by micro-organisms (such as bacteria,fungi, algae, protozoa and viruses). In addition, this course investigates the roles of plants and animals to produce useful products.

    BIOL-7006 -  Applied Molecular Genetics
    An advanced course in molecular genetics placing emphasis on the extraction and analysis of DNA from cells and tissues, cloning vectors, polymerase chain reaction, manipulation of plasmids, hybridization, nucleic acid sequencing and gene expression.

    BIOL-7007 -  Applied Biotechnology 1
    This course describes basic principles of recombinant DNA technology. It provides the student with detailed knowledge of recent developments in medical, agricultural,environmental and pharmaceutical aspects of biotechnology; transgenesis and animal bioreactors, human genome, DNA finger printing; social and ethical aspects of biotechnology through student-led seminars, and familiarity with Canadian and international patent laws.Professor: Kim Brookes ( hours: Please contact the instructor at the above e-mail to set up an appointment. Schedule and Location:D3014, Thursdays, 8 AM – 12 PM

    BIOL-7008 -  Bioinformatics
    Bioinformatics is a course that gives an introduction to the emerging scientific discipline that utilizes the combined power of biology,mathematics and computers.

    BIOL-7009 -  Applied Biotechnology 2

    This is an advanced course in biotechnology providing the student with detailed knowledge in both animal and plant tissue culture. Laboratories provide opportunities to apply techniques in staining, isolation and culturing of meristems, PCR. genetic mapping, and immunological techniques among others.

    BIOL-7010 -  Bioethics

    This is a course on the ethics, law and science of using new genetic technologies in medicine and agriculture, as well as, the current regulations governing this area both for companies and individuals.

    BIOL-7011 -  Current Topic in Biotechnology
    The course is designed to consolidate the students’ comprehension of biotechnology and written and oral communication skills. We will examine the present state of biotechnology through seminars, readings and field trips including a tour of a London-based Research Institute and Biotechnology Incubator. The field trips provide opportunities for students to apply professional communication and interpersonal skills in their interaction with industry experts and experience on site lecture sessions.

    BIOL-7012 -  Microbiology 3 (Immunology&Virology)
    This course provides the students with the knowledge of immune responses of cells and tissues of the lymphoid system as a key to control of diseases, an overview in virology including the animal, plant, insect and bacterial viruses, their classification; virus genome, viral replication and epidemiology.

    CHEM-7001 -  Biochemistry 2
    This course introduces the student to biosynthesis of macromolecules, bioenergetics and oxidative metabolism of carbohydrates, lipid, protein; biochemistry of hormones with clinical and nutritional correlations. The students are given the opportunity to perform laboratories inluding extraction, protein purification, isolation and separation of lipids, RNA and DNA.

    CHEM-7002 -  Chemistry 1
    This course covers the basic concepts of matter, quantitative interpretation of chemical reactions, behaviour of gases, composition of atoms and their electron configurations, and chemical bonding. Laboratories provide opportunities to develop techniques while working on experiments related to theory.

    CHEM-7003 -  Chemistry 2
    This course covers properties of liquids and solids with an emphasis on intermolecularforce and energy changes encountered when matter changes from one state to another or when solutions are prepared, an introduction to chemical kinetics andchemical equilibria, with an emphasis on acid-base and solubility equilibria, and electrochemical principles. Laboratories provide opportunities to develop techniques while working on experiments related to theory.

    CHEM-7004 -  Analytical Chemistry 1
    This course enables students to carry out stoichiometric calculations involving acid-base equilibria, change of oxidation state (redox reactions), precipitation and electrochemical processes. Students apply that knowledge in the preparation and standardization of analytical reagents and complex ion formation equilibria in the execution of a set selected, representative quantitative determinations of constituent chemical components in mixtures of unknown composition.

    CHEM-7005 -  Organic Chemistry 1

    This course introduces the students to a basic knowledge of alkanes, alkenes, alkynes and aromatic hydrocarbons. This includes their nomenclature, physical properties and characteristic chemical reactions.The laboratory work will emphasize the proper techniques of extraction, isolation, purification, identification and synthesis of simple organic compounds, as well as determination of their characteristic chemical reactions

    CHEM-7006 -  Biochemistry 1
    This is introductory course in Biochemistry introduces the student to the chemical diversity including biologically active versus inactive forms of macromolecules. The significance of nucleic acids to nuclear and nucleic acid associated organelles will be addressed. The role and interaction of macromolecules in overall cellular function is studied. What constitutes an enzyme and the diversity of functional activity, classification and their relevance to specific intracellular processes is emphasized. The laboratory components reflect qualitative and/or quantitative separation, identification and characterization of lipids, carbohydrates, proteins and nucleic acids.

    CHEM-7007 -  Instrumental Chemistry Analysis 1
    This course provides the student with a knowledge of concepts and techniques employed in the spectroscopic analysis of biological, chemical, environmental, forensic, medical and quality control samples. Practical experience will be provided in the operation of infrared (IR), ultraviolet/visible (UV/VIS), and atomic absorption (AA) spectrometers.

    CHEM-7008 -  Organic Chemistry 2
    This course builds upon the basic knowledge of alkanes, alkenes, alkynes and aromatic hydrocarbons from Organic Chemistry I. The functional groups covered in this course will be alcohols; phenols; thiols; ethers; alkyl halides; amines; aldehydes and ketones; carboxylic acids and their derivatives. The nomenclature, physical properties, characteristic chemical reactions and synthesis of compounds containing these functional groups will be studied.The laboratory work will emphasize the safe and proper laboratory techniques used to investigate the synthesis and characteristic properties of these functional groups.

    CHEM-7009 -  Instrumental Chemistry Analysis 2
    This course provides students with a knowledge of the concepts and techniques employed in chromatographic separations and mass spectrometry. practical experience is gained in the operation of gas chromatographs (GC), liquid chromatographs (LC) and mass spectrometers (MS).

    CHEM-7010 -  Analytical Chemistry 2
    This course deals with the analysis of carbohydrates, proteins, and lipids extracted from products made by biotechnology-based industrial processes. Sampling procedures and sample preparation methods are also considered, as well as the role of analytical data in industrial quality assurance and control.

    COMM-7001 -  Introductory Communications

    This course provides students with the communication tools and skills typically used in an applied science workplace. Students develop skills in research, and technical writing. They conduct both primary and secondary research, as well as analyze and organize information. Students gain skills with a variety of workplace documents including: memos, e-mails, letters, lab reports, incident and informal reports and formal reports. Students also gain a legal understanding of the documents they produce.

    COMM-7005 -  Research & Technical Writing
    This is a practically oriented writing course that teaches students to prepare technical reports in the field of science and particularly biotechnology. Students will learn the basics of technical writing by preparing a variety of technical communications, both individually and in teams.

    COMM-7006 -  Thesis
    This is an advanced, practically oriented course that teaches students to prepare an analytical technical report based on her/his experience during the previous work semester. Students submit a proposal to undertake additional research to support concrete practical data gained during the work experienced. Students will present summaries of their findings to their peers. Relevant employers or other industry professionals will be involved in the assessment of the final reports.

    COMP-7002 -  Computers & Applications
    This course uses MS Excel software to introduce spread sheets for data analysis and to solve statistical problems. Presenting data in a logical format for analysis will be emphasized. Arithmetic functions, conditional statements and graphic analysis will be applied. Matrix manipulations, macro writing and initiation to GenBank (National Center for Biotechnology Information) are also included.

    COMP-7003 -  Advanced Computer Applications

    This course builds on the previous mathematics and computer courses to permit the manipulation, computation and graphic display of results arising from major experimental databases. It uses

    ECON-7002 -  Macroeconomics

    This General education course covers a broad curriculum of macroeconomics principles. In presentation of each topic, a deliberate effort will be made to demonstrate how macroeconomic conditions can directly influence the operations and decision processes of business firms. Relevant examples are offered to illustrate how knowledge of macroeconomics can be applied in business.

    ENGR-7001 -  Bioprocess Engineering

    Bioprocess Engineering combines biotechnology training with core chemical engineering concepts to give an understanding of the application of the newest discoveries in molecular biology to large-scale production processes, and to solve problems related to industrial equipment design and operation for biological systems.

    ENGR-7002 -  Manufacturing Process Engineering

    This course will study the development and implementation of manufacturing processes and standards as well as ensuring efficiency and quality of products with an emphasis on problem solving and design in bioprocessing. Students will have the opportunity to visit a variety of biotechnology-related manufacturing settings.

    ENVR-7004 -  Environmental & World Issues

    This course is a comprehensive study of environmental issues and their effect on various ecosystems and the biosphere as a whole. The global impact of these issues combined with the economic, developmental, geographical, political and cultural influences will be examined. The importance of global sustainability and international governing bodies and agencies will be stressed.

    HIST-7003 -  History & Philosophy of Sciences

    In this course students will explore the history and philosophy of science from the 1600s to the present day. The early sciences of alchemy, astronomy and natural philosophy to present day theoretical physics, the discovery of DNA and the evolution of molecular biology will be examined. The relevance of conceptual and cultural themes to the history of science will be studied. Students will pursue the importance of philosophical questions related to theory evolution, testing and change. The nature of causation, laws and scientific methodologies and scientific explanations will be examined.

    MATH-7002 -  Mathematics 1
    This course is a review of algebraic concepts and introduction to calculus of one variable. The student will be introduced to the concepts of limits and continuity, the derivative and the integral. Students will master the techniques of differentiation and integration of polynomial and rational functions. In addition, problem solving will be emphasized with applications drawn from the biosciences wherever possible.

    MATH-7003 -  Mathematics 2

    The course is a continuation of the study of calculus developed in Mathematics I. After a brief review of differentiation techniques, this course examines the derivatives of transcendental functions including trigonometric, inverse trigonometric, exponential and ogarithmic forms. The second unit deals with the integrals of these functions and several techniques of integration including integration by simple substitution integration by parts, trigonometric substitution and partial fractions. The course ends with an introduction to the solution of first-order ordinary differential equations using separation of variables and use of the integrating factor. Throughout the course, students will be exposed to problem solving techniques including applications taken from the biosciences.

    MATH-7004 -  Statistics & Quality Assurance

    This course introduces correlation, regression, probability and probability distributions, statistical inference (with confidence intervals and significance tests). This course will use Excel and the Excel Stats ToolPak for graphical and numerical analysis

    PHRM-7002 -  Pharmacology,Toxicology,& Nutraceutical

    This is a survey course in pharmacology and toxicology dealing with the fundamentals of how xenbiotics produce toxic effects in biological systems with application of underlying principles in environmental control and risk assessment. Included are aspects of dose response relationship; routes of entry of xenobiotics and their fate in the organism; mechanisms of toxic action and methods for their assessment, with emphasis on chemical sensitization reactions, teratogenicity, mutagenicity and carcinogenicity. In addition to chemical hazards, risks of products of biotechnology will be discussed with reference to the manufacturing, marketing, advertising, labeling, and post-marketing surveillance for safety of pharmaceuticals and nutraceuticals.

    PHYS-7001 -  Physics 1
    This is an introductory course to prepare the student for more advanced Physics in the following semesters. The course covers the basic laws of Kinematics, Dynamics, Thermodynamics and Properties of Fluids. The material is partly calculus based with special emphasis on the solution of numerical problems. A total of six(6) laboratory exercises compliment the lecture material.

    PHYS-7002 -  Physics 2
    This course covers basic concept of wave motion, sound, electricity and magnetism, radiation, and atomic spectroscopy, as well as applications to instrumentation the student may encounter in the future. Six laboratory experiment compliment the lecture material.

    PHYS-7003 -  Radiation Physics
    This course covers the basic topics of radiation physics. The concepts relating to ionizing and non-ionizing are examined in detail. Those phenomena which are common over wide expanses of the electromagnetic spectrum - namely reflection, refraction, interference, diffraction and polarization are studied. X-rays and gamma rays are examined as examples of penetrating, ionizing forms of energy. Radioisotope techniques for biological labeling and the role of lasers in flow cytometry are also examined.

    SFTY-7001 -  Occupational Health & Safety

    This course is an introduction to risk assessment and management. Students learn to recognize and evaluate work place hazards and determine ways to control or alleviate these. Provincial and federal regulations and their relevance to the workplace are reviewed. Handling, storage, transport and the appropriate codes of conduct related to hazardous materials (biological and chemical) are examined.

    SFTY-7002 -  Biosafety & Regulatory Affair

    This course will ensure that students have the required knowledge to anticipate and manage risks associated with biotechnology settings. Relevant regulatory bodies, procedures, and requirements are covered.

    WRIT-7001 -  Report Writing
    This course builds on the foundation of the introductory communication course by expanding the students’ skills in the areas of research and academic writing as it applies to the workplace environment. Students master primary and secondary research techniques. They improve their ability to analyze, summarize, and integrate resource material into written reports. Students become thoroughly grounded in writing, editing and summarizing report materials and making oral presentations.

    ZOOL-7001 -  Animal Care & Handling

    This course will teach students the standard procedures for animal handling and use in experiments as advised by the Canadian Council of Animal Care (CCAC). A collaborative arrangement with an existing university animal facility will allow students to experience the appliaciton of theory learned in the classroom. The use of web-based/CD Rom learning modules will also be integrated into this course.

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